Key Findings on D-Ribose
- D-ribose is the most important non-glycemic sugar (does not raise blood sugar level) for the formation of ATP molecules – the power blocks in our cells.
- Different organs in the body require different concentrations of ATP and hence D-ribose. For example, the heart muscles require more ATP than the muscles of the limbs. This way the heart muscles can regenerate from energy loss faster and maintain an optimum cardiac rhythm.
- However, strenuous exercises leave muscle cell with more lactic acid than D-Ribose, and this is a cause of fatigue.
- Hence supplementing the body with D-ribose is important. Not only for athletes, but also for persons suffering from CFS or Fibromyalgia.
- Muscle biopsies have shown that levels of phosphocreatine (PCr) and ATP are significantly reduced (21% and 17%, respectively) in muscle tissues of fibromyalgia patients and the synthesis of PCr, an important store of cellular high-energy phosphates, is deficient. Magnetic imaging of skeletal muscle has shown that resting levels of ATP are 15% lower in fibromyalgia patients than in normal controls and during exercise PCr and ATP levels remain significantly low. However, supplementing the muscle with D-ribose has shown to elevate the energy levels of CFS patients in a pilot study. (R1)
- R1. Teitelbaum, J. E.; Johnson, C.; St Cyr, J., The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. Journal of alternative and complementary medicine 2006, 12 (9), 857-62.